Author

Hao Pan

Northwestern UniversityORCID 0000-0002-5543-4792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Adam W. T. SteffeckiD· 1 shared Ala A. ElmashaeiD· 1 shared Allegra C. MinoriD· 1 shared Andrew Hoffmann· 1 shared Andrew N. BortviniD· 1 shared Anmol SinghiD· 1 shared Avery Davis BelliD· 1 shared Caitlyn Elysse BrookinsiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Adam W. T. SteffeckORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A bivalent lysine-acetylated small-molecule binding site in MYC

Dikshat Gopal Gupta, Mihai Ioan Truica, Jin‐gon Shim, J. Brandon Parker, Mahil Lambert, Adam W. T. Steffeck, Daniel Herald Ryan, Hao Pan, Kerem Kahraman, Xinyan Lu, William Yang, Kenji Unno, Ala A. Elmashae, Megan M. Kerber, Caitlyn Elysse Brookins, , Sarki Abba Abdulkadir

This study identifies a bivalent binding site in MYC for small-molecule inhibitors and shows acetylation enhances inhibitor binding and oncogenic activity.

bioRxiv · Aug 18, 2026 · PreprintCancer Biology

AI-enabled Spatial Profiling of Circulating Tumor-Immune Ecosystems Predicts Patient Outcomes Across Cancers

Joshua R Squires, Yuanfei Sun, Andrew Hoffmann, Youbin Zhang, Hao Pan, Fangjia Tong, Yiwen He, David Scholten, Hannah Faisal Almubarak, Michael J. Gurley, Allegra C. Minor, Anmol Singh, James Zhang, Hannah Ding, Chengsheng Mao, , Huiping Liu

The paper develops an AI framework to analyze blood scans and predict patient outcomes by characterizing tumor-immune ecosystems in circulation.

bioRxiv · Jul 3, 2026 · PreprintCancer Biology

Strict adherence to Mendel's First Law across a large sample of human sperm genomes

Sara A. Carioscia, Kathryn J. Isaac, Andrew N. Bortvin, Hao Pan, Daniel Ariad, Avery Davis Bell, Rajiv C. McCoy

The paper analyzes human sperm genomes to test for transmission distortion, finding no evidence of weak TD and introducing a new method for low-coverage data.

eLife · Dec 7, 2022Peer-reviewedGenomics