Cancer BiologyTranslational OncologyPeer-reviewed
CDK4/6 inhibitors promote PARP1 degradation and act synergistically with PARP inhibitors in non-small cell lung cancer
Carlos M. Roggero, Anwesha B Ghosh, Anvita Devineni…·Yi Yin
This study shows CDK4/6 inhibitors promote PARP1 degradation and synergize with PARP inhibitors to kill NSCLC cells by enhancing DNA damage and apoptosis.
17 citations