Vincent Goffin

This study identifies castration-tolerant Club-like cells in prostate cancer and shows that targeting FOSL1/AP-1 and PIM kinases reduces their progenitor properties and tumor growth.

This study shows that beta2 adrenergic receptor stimulation increases neuroendocrine differentiation and reduces proliferation in BPH-1 cells, suggesting a link between adrenergic signaling and benign prostatic hyperplasia.

The paper re-analyzes scRNA-seq datasets to show that luminal progenitor clusters across studies overlap and matches FACS-enriched LSCmed cells in mice and humans.

This study identifies sex-specific neuroendocrine mechanisms in chronic pain, showing that prolactin receptor signaling in sensory neurons contributes to hyperalgesic priming in females but not males.