Qiushi Ye

This study identifies the flexible N-terminal domain of Sorcin as a critical regulator that enhances Ca2+ responsiveness by stabilizing its active conformation through dynamic contacts.

This study uses long-timescale molecular dynamics simulations to show that Ca2+ binding shifts pre-existing active states in Sorcin rather than inducing activation de novo.

This study investigates calcium-induced Sorcin aggregation using stopped-flow light scattering, finding that aggregation is reversible, cooperative, and concentration-dependent.