Molecular BiologyNature CommunicationsPeer-reviewed
HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex
Matthias S. Leisegang, Jasleen Kaur Bains, Sandra Seredinski…·Ralf Peter Brandes
The paper identifies HIF1α-AS1 as a DNA:DNA:RNA triplex-forming lncRNA that interacts with the HUSH complex to repress gene expression and modulates angiogenesis in pulmonary hypertension.
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