Chao‐Chung Kuo

This study identifies co-regulated DNA methylation patterns in leukemia and shows their presence in other cancer types, suggesting non-random, network-based epigenetic regulation.

This study investigates SMAD2's role in integrating TGF-β and antigen signaling in mast cells, showing its necessity for both anti-inflammatory and pro-inflammatory responses.

This study shows that DNMT1 regulates the migration of somatostatin-expressing interneurons, affecting cortical layer structure and function in mice.

The paper shows that loss of four extracellular matrix proteins in mice causes retinal dysfunction, impaired visual motion processing, loss of specific retinal cells, and synaptic imbalance.

RGT is a Python package for integrative analysis of regulatory genomics data, offering tools for peak calling, binding site prediction, and regulatory factor association.

The paper identifies HIF1α-AS1 as a DNA:DNA:RNA triplex-forming lncRNA that interacts with the HUSH complex to repress gene expression and modulates angiogenesis in pulmonary hypertension.

This study identifies DNA methylation changes during long-term cell culture that resemble epigenetic drift, linked to chromatin conformation changes.

This study develops a new epigenetic age prediction model based on stochastic DNA methylation patterns observed in targeted CpG sites using BBA-seq.