Author
Brejnev Muhizi Muhire
Van Andel InstituteORCID 0000-0002-5594-1348Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2026 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 17 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- Molecular BiologyRNA BiologyPeer-reviewed
Combined single-sample metabolomics and RNAseq reveals a hepatic pyrimidine metabolic response to acute viral infection
Zachary Madaj, Michael S. Dahabieh, Vijayvardhan Kamalumpundi…·Ryan D. Sheldon
This study integrates metabolomics and RNAseq from the same liver samples to show that prior metabolite extraction does not harm RNAseq quality and reveals pyrimidine metabolism as a key pathway in acute viral infection.
9 citations - Developmental BiologybioRxivPreprint
Stimulation-responsive enhancers regulate inflammatory gene activation through retention and modification of H2A.Z-variant accessible nucleosomes
Audrey Sporrij, Meera P. Prasad, Brejnev Muhizi Muhire…·Leonard Ira Zon
The paper identifies how dmPGE2 regulates inflammatory gene activation in HSPCs by modulating enhancer chromatin structure through H2A.Z-variant nucleosome retention and acetylation.