James D. Foster

This study shows that methamphetamine reduces DAT palmitoylation, linking this modification to transport down-regulation and suggesting its role in dopamine reuptake regulation.

This study investigates how palmitoylation modulates autism-associated serotonin transporter variants and shows that escitalopram can normalize their function.

This study shows that KOR antagonism restores phosphorylation, trafficking, and behavior in a mouse model with a disease-associated DAT variant.

This study shows that palmitoylation regulates norepinephrine transporter (NET) trafficking and expression, and that a POTS-associated NET mutant has reduced palmitoylation and surface expression.

This study shows that palmitoylation regulates SERT activity, trafficking, and expression, and that escitalopram reduces SERT palmitoylation, leading to decreased surface expression and transport capacity.