Yu Xia

The paper evaluates RNA-seq preprocessing pipelines to identify ABC transporters involved in taxane export in Taxus species, showing the importance of batch correction for accurate gene discovery.

The paper assesses how mutation-induced biophysical destabilization in the human structural protein interactome correlates with cancer-driving potential using fold difference metrics.

The paper analyzes selective pressures on virus-targeted host proteins by integrating PPI data and residue contacts, revealing spatial patterns of positive and negative selection across interaction interfaces.

FiGS-MoD identifies human signaling motifs by integrating residue features and HMMs, outperforming MEME and providing 221,840 SLiM predictions.

The paper predicts depression risk in early adolescents using multimodal brain imaging features and machine learning, finding that resting-state functional connectomes outperform other neuroimaging derivatives.

The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.

The paper identifies 2,280 essential genes in human B-cell lymphoma cells using an EKO library and RANKS tool, revealing context-specific essentiality and evolutionary patterns.