Adriana San‐Miguel

TAXISCAN improves chemotaxis assay throughput and behavioral depth in C. elegans by automating image acquisition and analysis.

This study uses automated dendrite tracing and categorization to show that aging and cold shock cause distinct dendritic beading patterns driven by branching history and systemic effects, respectively.

This study assesses PDMS toxicity in C. elegans, showing environmental and sterol-dependent effects of PDMS components and their leachates.

This study shows that Aβ in C. elegans increases resistance to heat and hypoxia via HSPs and neuropeptide signaling, but not oxidative stress.

This study engineers S. boulardii to control gene expression and gut residence time via diet-responsive systems, enabling precise therapeutic delivery in the mouse gut.

This paper shows that human trophoblast stem cells can be derived from term placenta CTBs using a modified medium, enabling diverse genetic hTSC lines for placental research.

The paper shows that morphological changes in dopaminergic neurons of C. elegans correlate with functional impairments, as worms with dendrite degeneration paralyze more in dopamine solutions.

This paper establishes a chemically defined culture system for differentiating human trophoblast stem cells into extravillous trophoblast and syncytiotrophoblast lineages, showing that laminin-1 switches differentiation fate.

This study quantifies DAF-16 spatiotemporal activity in C. elegans under dietary restriction and finds it predicts lifespan extension with 78% accuracy.

The paper derives two distinct trophectoderm stem cells from human pluripotent stem cells, showing differences in markers, culture requirements, and transcriptome profiles.

This study uses deep learning to analyze neurodegeneration patterns in C. elegans neurons, finding distinct effects of aging and cold-shock.

The paper presents HuRI, a comprehensive human protein-protein interaction map, and demonstrates its utility in understanding cellular function and disease mechanisms.