Heart-On-a-Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell- and Tissue-scale Contractile Stresses
Ali Mousavi, Christina-Marie Boghdady, Shihao Cui, Sabra Rostami, Amid Shakeri, Naimeh Rafatian, Mark R. P. Aurousseau, Grégor Andelfinger, Milica Radisic, Christopher Moraes, Houman Savoji
This paper introduces a heart-on-a-chip platform with ultrasoft mechanosensors to measure cell- and tissue-scale contractile stresses, showing that ECM composition affects contractility and drug responses.
Small · Dec 31, 2025Peer-reviewedBioengineering