Christopher Moraes

Stress-adaptive biomaterials with tunable yielding architectures regulate organoid morphogenesis

This study shows that tunable yield stress in biomaterials affects organoid morphogenesis, with optimal yield stress promoting specific developmental features.

Heart-On-a-Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell- and Tissue-scale Contractile Stresses

This paper introduces a heart-on-a-chip platform with ultrasoft mechanosensors to measure cell- and tissue-scale contractile stresses, showing that ECM composition affects contractility and drug responses.

Directed biomechanical compressive forces enhance fusion efficiency in model placental trophoblast cultures

The paper shows that mechanical compressive forces enhance fusion in trophoblast cell cultures, suggesting a role for biomechanics in placental development.

The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells

This study compares the demethylation efficacy and toxicity of GSK-3484862 and 5-azanucleosides in murine embryonic stem cells, finding GSK-3484862 induces more effective demethylation with less toxicity.