Roshan Kern

The paper identifies the proteasome's role in regulating CENP-T levels to prevent non-centromere kinetochore assembly.

Brieflow is a computational pipeline for analyzing optical pooled screening data, demonstrating its ability to recover biological modules missed by existing methods.

This paper predicts single-cell phenotypes from nuclear morphology using pre-labeled microscopy data, achieving high accuracy for some phenotypes but facing generalizability challenges.