Michael Gigl

De novo Rubisco design with protein language models

This paper designs novel Rubisco variants using protein language models, identifying active candidates with improved CO2/O2 specificity and structural validity.

Brassinosteroid-regulated transcription factors confer epigenetic changes that repress plant immunity

This study shows brassinosteroids repress plant immunity by inducing DNA methylation and altering splicing of immune receptor genes through bHLH transcription factors.

Diversification of ligand preference in conserved Brassicaceae LORE immune receptors matches proteobacterial 3-hydroxy fatty acid profiles

The paper investigates LORE receptor diversification in Brassicaceae, showing conserved 3-OH-FAs sensing but varied chain-length preferences matching bacterial profiles.

Transcriptome and hormone regulations shape drought stress-dependent Fusarium Head Blight susceptibility in different barley genotypes

The paper examines how drought stress and Fusarium infection interact to affect Fusarium Head Blight susceptibility in barley, finding that drought increases disease severity in moderately resistant genotypes but not in highly susceptible ones.

Skeletal muscle hypertrophy rewires glucose metabolism: an experimental investigation and systematic review

This study investigates metabolic changes during skeletal muscle hypertrophy using metabolomics and finds rewiring of glycolytic intermediates into anabolic pathways, particularly the serine synthesis pathway.