Author
University of GothenburgORCID 0000-0002-5633-2894Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
T.-R. J. King-Hudson, James S. Davies, Senwei Quan…·Renwick C. J. Dobson
This study solves the structure of the TRAP substrate-binding protein AaSiaP in different conformations, revealing how it binds N-acetylneuraminate and stabilizes a closed state.
Parveen Goyal, KanagaVijayan Dhanabalan, Mariafrancesca Scalise…·Subramanian Ramaswamy
The paper reports the structures of SiaQM from Fusobacterium nucleatum with and without Neu5Ac, revealing interactions and transport mechanisms.
James S. Davies, Michael J. Currie, Rachel A. North…·Renwick C. J. Dobson
The paper reports the cryo-EM structure of a TRAP transporter and elucidates its mechanism of sodium-driven substrate uptake.
Christopher R. Horne, Hariprasad Venugopal, Santosh Panjikar…·Renwick C. J. Dobson
This study elucidates how NanR represses sialic acid metabolism in E. coli by showing its cooperative DNA binding and allosteric regulation by N-acetylneuraminate.