Author
University of CanterburyORCID 0000-0003-1509-7581Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jeffery M. R. B. McAlpine, Jingyi Zhu, Nicholas Pudjihartono…·Adam J. Middleton
The paper identifies ubiquitin variants that inhibit Ube2d2, showing structural and biophysical properties that suggest potential for developing selective E2 enzyme inhibitors.
T.-R. J. King-Hudson, James S. Davies, Senwei Quan…·Renwick C. J. Dobson
This study solves the structure of the TRAP substrate-binding protein AaSiaP in different conformations, revealing how it binds N-acetylneuraminate and stabilizes a closed state.
James S. Davies, Michael J. Currie, Rachel A. North…·Renwick C. J. Dobson
The paper reports the cryo-EM structure of a TRAP transporter and elucidates its mechanism of sodium-driven substrate uptake.