Debasis Dash

This study shows methionine supplementation enhances pro-inflammatory responses and mycobacterial clearance in tuberculosis by modulating host metabolism and epigenetic pathways.

This study uses single-cell RNA-seq to show reduced type-II interferon and elevated Th17 responses in lung immune cells of diabetes-tuberculosis comorbid mice.

This paper introduces PgxSAVy, a tool for quality control of variant peptides in proteogenomics, which improves accuracy in identifying true variants and annotates their disease relevance.

The paper uses whole exome sequencing to show lower somatic mutation burden in vitiligo lesions, linked to reduced non-melanoma skin cancer risk through enhanced DNA repair.

The paper identifies genetic variations associated with three Ayurvedic constitution types using exome sequencing and computational methods, revealing actionable SNPs and genes with pleiotropic effects.

The paper identifies methylation changes in CAD-related genes in young patients compared to controls, suggesting potential epigenetic markers for CAD risk.

The paper investigates cellular responses to proteostasis impairments in yeast, finding that transcriptional responses often fail to restore proteostasis and that over-expression of alternative machineries can partially compensate for gene deletions.