Cell BiologybioRxivPreprint
Endolysosomal acidification amplifies JNK and IMD/NF-κB signaling and exacerbates oxidative injury in the Drosophila intestine
Douglas Terry, Liping Luo, Josh Lee, Brian Scott Robinson
This study shows that endolysosomal acidification worsens oxidative injury in Drosophila intestines by amplifying JNK and IMD/NF-κB signaling, and reducing V-ATPase levels protects against this damage.
DOI 10.64898/2026.07.28.740369