Hal S. Stern

Anhedonia buffers the effects of early-life unpredictability on threat-reward decision-making.

This study examines how anhedonia and early-life unpredictability interact to influence threat-reward decision-making in humans.

Sex-specific effects of early life unpredictability on hippocampal and amygdala responses to novelty in adolescents

This study examines how early-life unpredictability affects hippocampal and amygdala responses to novelty in adolescents, finding sex-specific differences in brain activation and functional connectivity.

Within-subject changes in DNA-methylome profile identify individual signatures of early-life adversity, with a potential to predict neuropsychiatric outcome.

This paper identifies DNA methylation changes in children linked to early-life adversity and shows their correlation with later executive function, with sex-dependent effects.

Integrity of the Uncinate Fasciculus Predicts Emotional Pattern Separation-Related fMRI Signals in the Hippocampal Dentate and CA3

The paper investigates how uncinate fasciculus integrity relates to hippocampal subregion activity during emotional pattern separation and links this to memory performance.

Intra-individual methylomics detects the impact of early-life adversity

The paper uses intra-individual DNA methylation analysis in rat buccal cells to show that early-life adversity alters methylation patterns predictive of gene repression and upregulation of inflammation and cell-fate pathways.