Author

Jason D. Arroyo

Pfizer (United States)ORCID 0000-0002-5674-6739Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:large language model· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Benjamin R. SabariiD· 1 shared Brooke A. ContiiD· 1 shared Chuong NguyeniD· 1 shared Daniel WongiD· 1 shared David J. ShieldsiD· 1 shared Deyan Tong· 1 shared Djork-Arné ClevertiD· 1 shared Evanthia E. PashosiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Benjamin R. SabariORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMar 6, 2026

Phenotypic reversion and target prioritization for cellular inflammation via representation learning with foundation models

Daniel Wong, Mary E. Piper, Jiao Qiao…·Evanthia E. Pashos

The paper uses single-cell foundation models to identify genetic targets that reverse inflammation in endothelial cells by analyzing Perturb-seq data with and without proinflammatory stimulation.

1 citation

humanscRNA-seq

𝕏 PostBluesky

Molecular BiologyeLifePeer-reviewedApr 7, 2025

N6-methyladenosine in DNA promotes genome stability

Brooke A. Conti, Leo Novikov, Deyan Tong…·Mariano Oppikofer

The paper identifies METTL3 and N6-methyladenosine (6mA) as factors promoting genome stability by repairing DNA base lesions.

7 citations

humanDNA methylation

𝕏 PostBluesky