Obesogenic diet impairs memory consolidation via the hippocampal endocannabinoid system
Eva‐Gunnel Ducourneau, Yoottana Janthakhin, José F. Oliveira da Cruz, Julien Artinian, Serge Alfos, Jean‐Christophe Helbling, Isabel Matias, Ioannis Bakoyiannis, Matéo N’diaye, Clémentine Bosch‐Bouju, Mylene Potier, Luigi Bellocchio, Arnau Busquets-García, Pierre Trifilieff, Giovanni Marsicano, Guillaume Ferreira
This study shows that an obesogenic diet impairs memory consolidation in mice via the hippocampal endocannabinoid system and mTOR pathway, which can be reversed by CB1R blockade or mTOR inhibition.
Current Biology · Nov 13, 2025Peer-reviewedNeuroscience