Arnau Busquets-García

Endocannabinoid-dopamine interactions mediate incidental associations in the hippocampus

This study investigates how endocannabinoid-dopamine interactions in the hippocampus mediate incidental associations, showing that CB1 receptors in D1-receptor-expressing cells are critical for IA formation.

Dentate gyrus and CA3 activity mediate light-tone second-order conditioning expression in mice

This study identifies the role of dentate gyrus and CA3 hippocampal regions in light-tone second-order conditioning in mice using chemogenetic inhibition and activity mapping.

Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species

This study shows that reducing Letm1 increases mitochondrial Ca2+ retention, overactivates metabolism, and enhances long-term memory in flies and mice.

Dorsal hippocampus mediates light-tone associations in male mice

This study develops a light-tone sensory preconditioning protocol in male mice to investigate hippocampal subregion involvement in higher-order conditioning and sex differences.

Obesogenic diet impairs memory consolidation via the hippocampal endocannabinoid system

This study shows that an obesogenic diet impairs memory consolidation in mice via the hippocampal endocannabinoid system and mTOR pathway, which can be reversed by CB1R blockade or mTOR inhibition.

Sex-dependent cortico-amygdala circuits controlling emotion recognition

This study identifies sex-dependent cortico-amygdala circuits for emotion recognition and shows that age-related impairments can be reversed in male mice through BLA activation.

Projecting neurons from lateral entorhinal cortex to basolateral amygdala mediate the encoding of incidental odor-taste associations

The paper identifies a novel brain circuit involving lateral entorhinal cortex to basolateral amygdala projections that mediate incidental odor-taste associations in mice.

Pregnenolone and AEF0117 block cannabinoid-induced hyperlocomotion through GSK3β signaling at striatopallidal neurons

This study shows that pregnenolone and AEF0117 block THC-induced hyperlocomotion by inhibiting CB1R-mediated GSK3β signaling in striatopallidal neurons.

Sex-specific maladaptive responses to acute stress upon in utero THC exposure are mediated by dopamine

This study investigates sex-specific effects of prenatal THC exposure on stress-induced dopamine dysfunction and sensorimotor gating in rats, showing a role for HPA axis and dopamine signaling.

A low repeated dose of Δ9-tetrahydrocannabinol affects memory performance through serotonergic signalling in mice

This study shows that repeated low-dose THC impairs memory in mice through serotonergic signaling via 5-HT2ARs, as evidenced by increased CB1R/5-HT2AR heterodimers and reduced LTP.

Astroglial calcium transfer from endoplasmic reticulum to mitochondria determines synaptic integration

The paper shows that mtCB1 receptor activation in astrocytes regulates calcium transfer from ER to mitochondria, influencing synaptic integration and plasticity.

Top-down control of water intake by the endocannabinoid system

The paper identifies a circuit involving endocannabinoid modulation of excitatory projections from the anterior cingulate cortex to the basolateral amygdala that promotes water intake.

Specific hippocampal interneurons shape consolidation of recognition memory

This study identifies a specific subclass of hippocampal interneurons that regulate recognition memory consolidation through CB1 receptor signaling and GABAergic inhibition.