Author

Lina-Marcela Díaz-Gallo

Karolinska University HospitalORCID 0000-0002-5688-0102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:simulation· 1

Frequent Co-Authors

Boel BrynedaliD· 2 shared Daniel RamsköldiD· 2 shared Helga WesterlindiD· 1 shared Karine CheminiD· 1 shared Klementy ShchetynskyiD· 1 shared Lars KlareskogiD· 1 shared Lars S. AlfredssoniD· 1 shared Lasse FolkerseniD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Boel BrynedalORCID

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2 papers

Recent·Most cited

Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations

Lina-Marcela Díaz-Gallo, Boel Brynedal, Helga Westerlind, Rickard Sandberg, Daniel Ramsköld

The paper simulates interactions between risk factors to assess additive and multiplicative models, finding that synergistic factors lead to multiplicative risks and thresholds create intermediate effects.

PLoS ONE · Apr 26, 2021Peer-reviewedGenetics

The association between the HLA-DRB1 shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions.

Lina-Marcela Díaz-Gallo, Daniel Ramsköld, Klementy Shchetynsky, Lasse Folkersen, Karine Chemin, Boel Brynedal, Steffen Uebe, Yukinori Okada, Lars S. Alfredsson, Lars Klareskog, Leonid Padyukov

The paper shows that HLA-DRB1 shared epitope alleles' risk for ACPA-positive RA is significantly influenced by interactions with non-HLA SNPs.

Annals of the Rheumatic Diseases · Jul 2, 2018Peer-reviewedGenetics