Author

Karine Chemin

Karolinska University HospitalORCID 0000-0002-2597-7809Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Annika van Vollenhoven· 1 shared Antonella NotarnicolaiD· 1 shared Begum HoruluogluiD· 1 shared Boel BrynedaliD· 1 shared Caroline GrönwalliD· 1 shared Daniel RamsköldiD· 1 shared Deniz Demirdal· 1 shared Edvard WigreniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Annika van Vollenhoven

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3 papers

Recent·Most cited

Anti-MDA5 monoclonal antibodies from patients with dermatomyositis - B cell characteristics and differential targeting of the helicase domains

Eveline Van Gompel, Marina Galesic, Nicolas Delaroque, Karolin Kern, Ragnhild Stålesen, Antonella Notarnicola, Deniz Demirdal, Monika Hansson, Annika van Vollenhoven, Edvard Wigren, S. Gräslund, Michael Szardenings, Vivianne Malmström, Ingrid E. Lundberg, Begum Horuluoglu, , Vijay Joshua

The paper identifies anti-MDA5 monoclonal antibodies from DM patients, showing they target distinct epitopes within the helicase domains of MDA5.

Journal of Autoimmunity · Feb 19, 2026Peer-reviewedImmunology

AI-Driven Virtual Screening and First-in-Class Conformational Biosensor Enable the Discovery of a GPR183 Inverse Agonist

Louise Andersson, Michele Roggia, Kittikorn Wangriatisak, Maria P. Gil, Karine Chemin, Sandro Cosconati, Paweł Kozielewicz

The paper discovers a GPR183 inverse agonist using AI-driven virtual screening and a conformational biosensor, showing inhibition of Gi activation and β-arrestin2 recruitment.

bioRxiv · Jun 19, 2025 · PreprintPharmacology & Toxicology

The association between the HLA-DRB1 shared epitope alleles and the risk of rheumatoid arthritis is influenced by massive gene-gene interactions.

Lina-Marcela Díaz-Gallo, Daniel Ramsköld, Klementy Shchetynsky, Lasse Folkersen, Karine Chemin, Boel Brynedal, Steffen Uebe, Yukinori Okada, Lars S. Alfredsson, Lars Klareskog, Leonid Padyukov

The paper shows that HLA-DRB1 shared epitope alleles' risk for ACPA-positive RA is significantly influenced by interactions with non-HLA SNPs.

Annals of the Rheumatic Diseases · Jul 2, 2018Peer-reviewedGenetics