Daniel Ramsköld

The paper simulates interactions between risk factors to assess additive and multiplicative models, finding that synergistic factors lead to multiplicative risks and thresholds create intermediate effects.

This paper introduces Smart-seq3, a single-cell RNA sequencing method that enables allele- and isoform-resolution RNA counting, showing improved sensitivity and isoform regulation detection in mouse and human samples.

The paper shows that HLA-DRB1 shared epitope alleles' risk for ACPA-positive RA is significantly influenced by interactions with non-HLA SNPs.