Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening
Li Zhang, Fen Hu, Zirong Zhao, Xinfeng Li, Mingyue Zhong, Jiajun He, Fangfang Yao, Xiaomei Zhang, Yuxuan Mao, Hongping Wei, Jin He, Hang Yang
The paper identifies hyper-thermostable peptidoglycan hydrolases from bacterial proteomes using lysin-derived antimicrobial peptide screening and shows their potent bactericidal activity.
eLife · Nov 26, 2024Peer-reviewedBiochemistry