Author

Yuxuan Mao

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Yijie GengiD· 2 shared Aiden F EnoiD· 1 shared Ally Xinyi Kong· 1 shared Baixi HeiD· 1 shared Binjie LiiD· 1 shared Catherine Hong· 1 shared Cory W. Holgren· 1 shared Dominic E. FullenkampiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersNeuroscience

Yijie GengORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mesoscale Soft Robotics for Mechanically Perturbing and Functionally Monitoring Responses in Human Organoids

Woo‐Youl Maeng, Zengyao Lv, Yasaman Samei, Kyoungho Ha, Kyung Su Kim, Lakshmi P. Prabakar, Ivana A. Chychula, Vasant Iyer, Binjie Li, Yuxuan Mao, Shengwei Xu, Tae Wan Park, Shupeng Li, Cory W. Holgren, Young Jin Jo, , John A. Rogers

This paper introduces a mesoscale soft robotic interface to apply mechanical forces to human organoids and monitor their physiological responses, revealing distinct mechanical and electrophysiological behaviors in cortical and cardiac organoids.

bioRxiv · Oct 30, 2026 · PreprintBioengineering

Top2a-dependent neuronal regulation of social behavior and persistent rescue of social deficit through PRC2-mediated epigenetic reprogramming

Baixi He, Yuxuan Mao, Catherine Hong, Yijie Geng

This study shows that neuronal Top2a regulates social behavior in mice, and PRC2 inhibition can rescue social deficits through epigenetic reprogramming.

bioRxiv · Feb 26, 2026 · PreprintNeuroscience

Butyrate rescues chlorpyrifos-induced social deficits through inhibition of class I histone deacetylases

Leonardo Diaz, Ally Xinyi Kong, Ping Zhang, Jinhua Chi, Khoa Trong Pham, Maja Johnson, Aiden F Eno, Isabelle Douglas, Yuxuan Mao, James W. MacDonald, Julia Yue Cui, Theo K. Bammler, Haiwei Gu, Yijie Geng

The paper shows that butyrate rescues CPF-induced social deficits in zebrafish by inhibiting class I HDACs, linking CPF exposure to gut microbiome, metabolome, and epigenetic changes.

bioRxiv · Oct 19, 2025 · PreprintNeuroscience

Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening

Li Zhang, Fen Hu, Zirong Zhao, Xinfeng Li, Mingyue Zhong, Jiajun He, Fangfang Yao, Xiaomei Zhang, Yuxuan Mao, Hongping Wei, Jin He, Hang Yang

The paper identifies hyper-thermostable peptidoglycan hydrolases from bacterial proteomes using lysin-derived antimicrobial peptide screening and shows their potent bactericidal activity.

eLife · Nov 26, 2024Peer-reviewedBiochemistry