Author

Ashwin Unnikrishnan

UNSW SydneyORCID 0000-0001-5168-8755Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

John E. PimandaiD· 2 shared Alicia Stein· 1 shared Berthold GöttgensiD· 1 shared Brendan LeeiD· 1 shared Carl Andrew PoweriD· 1 shared Chong Gao· 1 shared Chris Brownlee· 1 shared Daniel Geoffrey TeneniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

John E. PimandaORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 28, 2025

NPM1 mislocalization mediated by RNA Pol I inhibition alters chromatin landscape

Pierre Olivier Esteve, Sagnik Sen, Karthikeyan Raman…·Sriharsa Pradhan

The paper shows RNA Pol I inhibition disrupts nucleolar structure, alters NPM1 localization, and changes chromatin landscape through histone modifications and DNA methylation.

DOI 10.1101/2025.10.28.684736

humanChIP-seq

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Developmental BiologyNature Cell BiologyPeer-reviewedJul 28, 2022

Mesoderm-Derived PDGFRA+ Cells Regulate the Emergence of Hematopoietic Stem Cells in the Dorsal Aorta

Vashe Chandrakanthan, Prunella Rorimpandey, Fabio Zanini…·John E. Pimanda

The paper shows that mesoderm-derived PDGFRA+ stromal cells in the AGM region support endothelial-to-hematopoietic transition and LT-HSC generation.

36 citationstop 3%

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintJul 10, 2020

Induction of a SALL4-dependency for targeted cancer therapy

Junyu Yang, Chong Gao, Miao Liu…·LI Chai

This study shows that SALL4 can be induced in cancer cells to make them dependent on it, enabling targeted therapy with drugs like DAC and ENT.

DOI 10.1101/2020.07.10.197434

humanexperimental assay

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GeneticsbioRxivPreprintOct 17, 2019

The RNA Atlas, a single nucleotide resolution map of the human transcriptome

Lucía Lorenzi, Hua‐Sheng Chiu, Francisco Avila Cobos…·Pieter Mestdagh

The paper presents a comprehensive human transcriptome atlas with single-nucleotide resolution, identifying thousands of novel RNA species and regulatory interactions.

10 citations

humanbulk RNA-seq

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