Katharina Schmidt‐Bleek

The paper evaluates multi-laboratory studies to identify promising treatments by assessing effect sizes and experimental rigor across different medical fields.

This paper develops 3D patterned alginate-collagen hydrogels that spatially guide endothelial cell invasion and proliferation by controlling collagen fibrillogenesis, degradation, and viscoelasticity.

This study identifies a cortical niche-specific macrophage subset that drives early osteoclastogenesis in bone healing through spatial immune-stromal interactions in young mice.

This study shows that ECM viscoelastic properties in bone fracture hematoma influence macrophage polarization, with high stress relaxation time promoting pro-inflammatory and low promoting anti-inflammatory responses.

This paper shows that anisotropic hydrogel degradation patterns enhance hMSC alignment, mechanotransduction, and osteogenic differentiation compared to uniform materials.

The paper uses AI-based clustering to identify immune cell subtypes in fracture hematoma and bone marrow of mice, revealing differences between osteoporotic and non-osteoporotic groups.