Pasquale Pellegrini

Multi-Lab Testing of Early Preclinical Discoveries Identifies Promising Treatments

The paper evaluates multi-laboratory studies to identify promising treatments by assessing effect sizes and experimental rigor across different medical fields.

Set-up, validation, evaluation, and cost-benefit analysis of an AI-assisted assessment of responsible research practices in a sample of life science publications

This paper evaluates the use of LLMs to assess responsible research practices in scientific papers, finding comparable accuracy to single human reviewers but with variable performance across different practices.

Lack of p62 impairs glycogen aggregation and exacerbates pathology in a mouse model of myoclonic epilepsy of Lafora

This study shows that p62 is involved in Lafora body formation and that its absence reduces glycogen aggregation in muscle and heart but worsens brain pathology in a mouse model of Lafora disease.