Molecular BiologyJournal of Biological ChemistryPeer-reviewed
Proteasomal regulation of ASK family kinases dictates cell fate under hyperosmotic stress
Xiangyu Zhou, Kengo Watanabe, Kazuhiro Morishita…·Hidenori Ichijo
This study shows that proteasome activity inactivates ASK3 by degrading ASK1, linking proteasome function to cell survival under hyperosmotic stress.
DOI 10.1016/j.jbc.2025.110566