Valeria de Turris

This paper introduces a microfluidic-assisted 3D bioprinting system that enables precise control over cell compartmentalization and material composition for creating interconnected, functional tissue constructs.

This study uses patient-derived iPSCs with a GNAO1 variant to show altered neuronal differentiation and function in cortical neurons.

This study shows that HuD overexpression impairs neuromuscular junctions and induces apoptosis in ALS models, while its knockdown rescues these defects.

This study shows that microglia regulate glutamatergic synapses in adult mouse hippocampus, with their removal causing reversible synaptic and behavioral changes.

This study creates 2D and 3D human FXS models using FMRP-KO iPSCs, showing altered gene expression, impaired differentiation, and increased glial proliferation.

This study shows that ALS-FUS mutations disrupt HuD/ELAVL4 and FMRP activities, leading to axon phenotypes in motoneurons through altered transcript stability.