Author

Silvia Ghirga

Italian Institute of TechnologyORCID 0000-0002-7748-3704Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Chiara D’AntoniiD· 2 shared Federica CordellaiD· 2 shared Silvia Di AngelantonioiD· 2 shared Alessandro RosaiD· 1 shared Alessandro SolopertoiD· 1 shared Angelo M. ReggianiiD· 1 shared Carlo BrighiiD· 1 shared Debora SalernoiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Chiara D’AntoniORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Bezafibrate treatment rescues neurodevelopmental and neurodegenerative defects in 3D cortical organoid model of MAPT frontotemporal dementia

Federica Cordella, Lorenza Mautone, Debora Salerno, Lucrezia Tondo, Silvia Ghirga, Chiara D’Antoni, Erika Parente, Maria Anele Romeo, Mara Cirone, Paola Bezzi, Silvia Di Angelantonio

Alzheimer s & Dementia · Aug 1, 2025Peer-reviewedNeuroscience

Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

Carlo Brighi, Federico Salaris, Alessandro Soloperto, Federica Cordella, Silvia Ghirga, Valeria de Turris, Maria Rosito, Pier Francesca Porceddu, Chiara D’Antoni, Angelo M. Reggiani, Alessandro Rosa, Silvia Di Angelantonio

This study creates 2D and 3D human FXS models using FMRP-KO iPSCs, showing altered gene expression, impaired differentiation, and increased glial proliferation.

Cell Death and Disease · May 15, 2021Peer-reviewedNeuroscience