Author

Xiao Huang

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Arman Esshaghi BayatiD· 1 shared Bin XiaoiD· 1 shared Carl Johannes KoschmanniD· 1 shared Charles B. StevensoniD· 1 shared Dazhuan Eric XiniD· 1 shared Emily DengiD· 1 shared Fangze Qian· 1 shared Gao WentaoiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

Arman Esshaghi BayatORCID

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4 papers

Recent·Most cited

Co-evolution of Oncogenic KRAS Signaling and LILRBhigh Macrophages Drives Pancreatic Cancer Recurrence

Jianzhen Lin, Zhenzhen Xun, Fangze Qian, Zhigao Chen, Weikang Hu, W. Liu, Yang Wu, Hao Yuan, Lingdi Yin, Yuxing Wang, Xiao Huang, Yujia Dang, Bin Xiao, Junli Wu, Gao Wentao, , Han Liang

This study identifies a co-evolved tumor-immune interaction involving KRAS signaling and LILRBhigh macrophages that drives PDAC recurrence and presents a therapeutic strategy targeting this axis.

bioRxiv · Mar 7, 2026 · PreprintCancer Biology

A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma

Emily Deng, Xiaowen Zhong, Dazhuan Eric Xin, Upendra Kumar Soni, Wenkun Ma, Xiao Huang, Mingjun Cai, Po-Yu Liang, Jun Bai, Qian Qin, Shreya V. Mishra, Ming Hu, Arman Esshaghi Bayat, Jiajie Diao, Mei Xin, , Q. Richard Lu

This study identifies tonic signaling as a key factor in CAR-T cell efficacy for diffuse midline glioma, showing that restrained tonic signaling improves therapeutic outcomes.

bioRxiv · Sep 29, 2025 · PreprintCancer Biology

Tachykinin1-expressing neurons in the parasubthalamic nucleus control active avoidance learning

Ruining Hu, Nannan Wu, Tong Liu, Liuting Zou, Shiyu Lv, Xiao Huang, Rongfeng K. Hu

This study identifies the parasubthalamic nucleus and its Tac1-expressing neurons as critical for active avoidance learning through optogenetic and imaging experiments.

bioRxiv · Nov 3, 2024 · PreprintNeuroscience

Pumilio Proteins Exert Distinct Biological Functions and Multiple Modes of Post-Transcriptional Regulation in Embryonic Stem Cell Pluripotency and Early Embryogenesis

Katherine E. Uyhazi, Yiying Yang, Na Liu, Hongying Qi, Xiao Huang, Winifred Mak, Scott D. Weatherbee, Xiaoling Song, Haifan Lin

This study identifies distinct roles of Pum1 and Pum2 in ESC pluripotency and embryogenesis, revealing novel post-transcriptional regulatory mechanisms.

bioRxiv · Aug 30, 2019 · PreprintDevelopmental Biology