Author

Emanuela Gadaleta

Queen Mary University of LondonORCID 0000-0002-5740-6293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Claude ChelalaiD· 3 shared J. Louise JonesiD· 2 shared Maryam AbdollahyaniD· 2 shared Abu Z M Dayem UllahiD· 1 shared Faraz K. MardakhehiD· 1 shared Graeme J. ThorniD· 1 shared Ivan T. GoutiD· 1 shared Jorge OscanoaiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMolecular Biology

Claude ChelalaORCID

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Author profile →

3 papers

Recent·Most cited

Coenzyme A homeostasis regulates hypoxic signalling via UBFD1in triple-negative breast cancer

Paul Grevitt, Óscar Maiques, Kunal Shah, Valle Morales, Emanuela Gadaleta, Martin Dodel, Katiuscia Bianchi, Ivan T. Gout, J. Louise Jones, Claude Chelala, Michael J. Plevin, Faraz K. Mardakheh, Tyson V. Sharp

This study identifies CoAsy as a regulator of HIF signalling in TNBC, showing its loss stabilizes HIF-1 and HIF-2 and correlates with poor patient outcomes.

bioRxiv · Jun 18, 2025 · PreprintMolecular Biology

The clinical and molecular landscape of breast cancer in women of African and South Asian ancestry

Graeme J. Thorn, Emanuela Gadaleta, Abu Z M Dayem Ullah, Lewis G. E. James, Maryam Abdollahyan, Rachel Barrow‐McGee, J. Louise Jones, Claude Chelala

This study examines breast cancer differences between African, South Asian, and European ancestries, finding earlier onset, different tumor characteristics, and varied mutation patterns.

Nature Communications · May 20, 2025Peer-reviewedGenetic & Genomic Medicine

SNPnexus COVID: Facilitating the analysis of COVID-19 host genetics

Jorge Oscanoa, Lavanya Sivapalan, Maryam Abdollahyan, Emanuela Gadaleta, Claude Chelala

SNPnexus COVID provides a web-based platform for analyzing genetic variants in COVID-19 patient genomes to prioritize clinically relevant variants for prevention and treatment.

bioRxiv · Dec 18, 2020 · PreprintGenomics