Author
Centre Hospitalier Universitaire VaudoisORCID 0000-0002-5744-4142Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Alice Bruel, Lina Bacha, Emma Boehly, Constance De Trogoff, Luca Represa, Grégoire Courtine, Auke Jan Ijspeert
The paper investigates how spinal pathways and supraspinal commands modulate upper limb control in different gravity conditions using neuromusculoskeletal simulations.
PLoS Computational Biology · Jan 6, 2025Peer-reviewedNeuroscience
Alan Yue Yang Teo, Matthieu Gautier, Laurent Pierre Brock, Jennifer Tsai, Alexandra de Coucy, Achilleas Laskaratos, Nicola Regazzi, Quentin Barraud, Michael V. Sofroniew, Mark A. Anderson, Grégoire Courtine, Jordan W. Squair, Michael A. Skinnider
The paper introduces Vespucci, a machine-learning method for identifying perturbation-responsive regions and genes in spatial transcriptomics data, showing it outperforms existing methods.
bioRxiv · Jun 13, 2024 · PreprintBioinformatics
Jan Elaine Soriano, Rémi Hudelle, Loïs Mahe, Matthieu Gautier, Alan Yue Yang Teo, Michael A. Skinnider, Achilleas Laskaratos, Steven Ceto, Claudia Kathe, Thomas Haynes Hutson, Rebecca Charbonneau, Fady Girgis, Steve Casha, Julien Rimok, Marcus Tso, , Grégoire Courtine
This study identifies neuronal architectures responsible for autonomic dysreflexia after spinal cord injury and demonstrates how epidural stimulation can counteract it in mice, rats, and humans.
bioRxiv · May 6, 2024 · PreprintNeuroscience
Michael A. Skinnider, Matthieu Gautier, Alan Yue Yang Teo, Claudia Kathe, Thomas Haynes Hutson, Achilleas Laskaratos, Alexandra de Coucy, Nicola Regazzi, Viviana Aureli, Nicholas D. James, Bernard Laurent Schneider, Michael V. Sofroniew, Quentin Barraud, Jocelyne Bloch, Mark A. Anderson, , Grégoire Courtine
The paper introduces the Tabulae Paralytica, a multimodal atlas of spinal cord injury, revealing biological principles and developing a gene therapy to restore walking in old mice.
bioRxiv · Jun 23, 2023 · PreprintGenomics
Jordan W. Squair, Matthieu Gautier, Claudia Kathe, Mark A. Anderson, Nicholas D. James, Thomas Haynes Hutson, Rémi Hudelle, Taha Qaiser, Kaya J.E. Matson, Quentin Barraud, Ariel J. Levine, Gioele La Manno, Michael A. Skinnider, Grégoire Courtine
This study evaluates differential expression methods in single-cell transcriptomics, finding that many produce false discoveries due to ignoring biological variation.
Nature Communications · Sep 28, 2021Peer-reviewedBioinformatics
Kaya J.E. Matson, Daniel E. Russ, Claudia Kathe, Dragan Maric, Isabelle Hua, Jonathan Krynitsky, Randall H. Pursley, Anupama Sathyamurthy, Jordan W. Squair, Grégoire Courtine, Ariel J. Levine
The paper profiles single nucleus RNA-seq data from spinal cord tissue after injury to identify repair-related cellular mechanisms and potential therapeutic targets.
bioRxiv · Apr 28, 2021 · PreprintNeuroscience
Matthew G. Perich, Sara Conti, Marion Badi, Andrew R. Bogaard, Beatrice Barra, Kanaka Rajan, Jocelyne Bloch, Grégoire Courtine, Silvestro Micera, Marco Capogrosso, Tomislav Milekovic
Recordings from four monkeys handling objects place input-driven activity in one putative somatosensory-feedback subspace of motor cortex, prominent around error correction and probed by stimulating ascending tracts.
bioRxiv · Jul 30, 2020 · PreprintNeuroscience
Michael A. Skinnider, Jordan W. Squair, Claudia Kathe, Mark A. Anderson, Matthieu Gautier, Kaya J.E. Matson, Marco Milano, Thomas Haynes Hutson, Quentin Barraud, Aaron Alexander Phillips, Leonard J. Foster, Gioele La Manno, Ariel J. Levine, Grégoire Courtine
The paper introduces a machine-learning method, Augur, to identify cell types most responsive to biological perturbations in single-cell data and validates it on multiple datasets.
Nature Biotechnology · Jul 20, 2020Peer-reviewedGenomics