Sebastien M. Weyn‐Vanhentenryck

The paper develops a computational method, mCross, to model RBP binding specificity using precise crosslink site registration and validates it with ENCODE eCLIP data.

This study identifies Dazl's role in germ cell survival by mapping its RNA interactions and showing its regulation of genes critical for proliferation and survival.

The paper identifies a GAU motif recognized by LIN28's CSD domain, which enhances let-7 microRNA suppression in Class I precursors, contributing to development and cancer.

The paper identifies early- and late-switch exons in neural development and shows they are regulated by RNA-binding proteins, with some neuronal subtypes lacking these regulators and retaining an immature splicing program.