Author
Case Western Reserve UniversityORCID 0000-0003-1476-9059Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Robert Buschauer, Yoshitaka Matsuo, Takato Sugiyama…·Roland Beckmann
The paper shows the Ccr4-Not complex interacts with the ribosome's E-site when codon optimality is low, linking translation efficiency to mRNA stability.
Megan E. Forrest, Ashrut Narula, Thomas J. Sweet…·Olivia S. Rissland
The paper shows that codon usage and amino acid identity significantly influence mRNA stability in humans, affecting protein abundance through translational elongation rates.
Leah L. Zagore, Thomas J. Sweet, Molly M. Hannigan…·Donny D. Licatalosi
This study identifies Dazl's role in germ cell survival by mapping its RNA interactions and showing its regulation of genes critical for proliferation and survival.
Gavin K. Hanson, Najwa Alhusaini, Nathan J. Morris…·Jeff M. Coller
The paper shows that faster translation elongation on optimal codons increases mRNA stability in yeast, with A-site tRNA decoding being the key factor driving mRNA decay.