Author

Cristián Sandoval-Acuña

Czech Academy of Sciences, Institute of BiotechnologyORCID 0000-0002-5760-0985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Jan ŠtursaiD· 1 shared Jaroslav TruksaiD· 1 shared Kristýna BlažkováiD· 1 shared Kristýna Klanicová· 1 shared Lukáš WerneriD· 1 shared Petra Potomova· 1 shared Radislav SedláčekiD· 1 shared Sukanya B. JadhaviD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Jan ŠtursaORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJan 17, 2024

Selective killing of cancer cells via simultaneous destabilization of mitochondrial iron metabolism and induction of ferroptosis elicited by mitochondrially targeted iron chelator deferasirox

Sukanya B. Jadhav, Cristián Sandoval-Acuña, Yaiza Pacior…·Jaroslav Truksa

This study introduces mitoDFX, a mitochondrially targeted iron chelator that simultaneously depletes iron and induces ferroptosis, showing high selectivity and efficacy against cancer cells.

3 citations

humanmetabolomics

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