NeurosciencebioRxivPreprint
Targeting mTOR restores tau-induced metabolic, mitochondrial, and cognitive deficits in a tauopathy mouse model
Zhi Tang, Min Guo, Yuanting Ding…·Xiaolan Qi
This study shows that mTOR inhibition with rapamycin improves cognitive function and metabolic profiles in a tauopathy mouse model by reducing tau phosphorylation and mitochondrial dysfunction.
DOI 10.1101/2024.11.24.625068