Author

Sarah Allen

University of BernORCID 0000-0002-5776-4285Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sarah Allen1 paper · University of Dundee

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

Anastasia KhvorovaiD· 2 shared Ashley SummersiD· 2 shared Eric LuuiD· 2 shared Jillian BelgradiD· 2 shared Raymond C. FurgaliD· 2 shared Alan G. HendrickiD· 1 shared Allison MaebiusiD· 1 shared Brian TraniD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Anastasia KhvorovaORCID

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3 papers

Recent·Most cited

Mismatch repair dissection by in vivo RNAi reveals dose-dependent modulators of somatic instability and proteome remodeling in Huntingtons disease

Jillian Belgrad, Todd M. Greco, Ellen Sapp, Ashley Summers, Daniel O’Reilly, Eric Luu, Josiah E. Hutton, Nozomi Yamada, Hassan H. Fakih, Raymond C. Furgal, Dimas Echeverria, Nicholas McHugh, Brianna M. Bramato, Chantal Ferguson, Samuel R. Hildebrand, , Anastasia Khvorova

The paper uses RNAi to identify dose-dependent MMR gene modulators of somatic instability and proteome changes in HD mouse models.

bioRxiv · Jun 25, 2026 · PreprintNeuroscience

N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletion

Xiaodong Li, Sarah Allen, Liping Lyu, Sebastian T. Bechara, Engeroff Cristina, Alan G. Hendrick, Mariusz Nowacki

The paper shows that 6mA methylation in Paramecium protects host DNA from deletion during development and is inherited transgenerationally.

bioRxiv · Feb 16, 2026 · PreprintCell Biology

High-throughput quantification of huntingtin mRNA expression and aggregation in mouse brain using automated RNAscope imaging.

Pieter van Velde, Brian Tran, Sarah M. Allen, Eric Luu, Raymond C. Furgal, Ashley Summers, Jillian Belgrad, Emily G. Knox, Anastasia Khvorova, David Grünwald

This study quantifies huntingtin mRNA expression and aggregation in mouse brains using a high-throughput RNAscope pipeline, revealing heterogeneity in mRNA accumulation and localization across brain regions.

bioRxiv · Feb 11, 2026 · PreprintCell Biology