Viviana Scoca

The paper identifies multi-hit STAG2 mutations in MDS patients, showing they are associated with worse outcomes and suggest convergent evolutionary targeting of the cohesin gene.

This study investigates how Stag2-dependent chromatin remodeling influences Gata1's function in erythropoiesis, revealing its role in lineage-specific gene regulation and dyserythropoiesis in MDS.

The paper develops a fluorescence microscopy method to track HIV-1 DNA in vivo, revealing active and silent viral genomes in humanized mice tissues.

This study shows that cohesin mutations alter chromatin accessibility, enhancing FLI1-Menin interaction and promoting leukemogenesis through therapeutic vulnerabilities.