Andrew D. Rhim

This study shows that Adar1 deletion in mice causes exocrine pancreas degeneration through Mavs-dependent interferon signaling, which is rescued by concurrent Mavs deletion.

This study evaluates the diagnostic sensitivity of the MED-Amp assay for detecting rare KRAS mutations in ctDNA from localized pancreatic cancer patients, showing improved detection at low DNA input and correlation with survival outcomes.