Author

Stéphen Manon

Centre National de la Recherche ScientifiqueORCID 0000-0002-5792-1084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

Muriel PriaultiD· 3 shared Akandé Rouchidane EyitayoiD· 2 shared Joann KervadeciD· 2 shared Adrien MahleriD· 1 shared Agathe Hubert· 1 shared Axel Boudier-Lemosquet· 1 shared Cécile Dahout-GonzaleziD· 1 shared Charlène Dupont· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBiochemistry

Muriel PriaultORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 19, 2026

Production of membrane-embedded Bcl-2 proteins - Use of cell-free synthesis in continuous exchange for co-translational insertion of Bcl-2 proteins in lipid bilayer nanodiscs

Joann Kervadec, Akandé Rouchidane Eyitayo, Cécile Dahout-Gonzalez…·Muriel Priault

This paper describes methods to produce membrane-embedded Bcl-2 family proteins using cell-free synthesis in lipid bilayer nanodiscs for structural and functional studies.

DOI 10.64898/2026.08.15.745005

protein structureexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJul 17, 2026

VDAC2 stabilizes a membrane-inserted, primed intermediate of BAX activation

Varun Ravishankar, Laidy M. Alvero-González, Agathe Hubert…·Lucie A. Bergdoll

This study identifies VDAC2 as a regulator of BAX activation by stabilizing a primed, membrane-inserted intermediate in the BAX activation pathway.

DOI 10.64898/2026.07.13.738215

humanstructural biology

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BiochemistrybioRxivPreprintMay 16, 2026

Molecular determinants of Bcl-xL membrane insertion - Structural plasticity exploration in solution and in nanodiscs identifies IsoAsp deamidation as a loss-of function mechanism in vivo.

Joann Kervadec, Maria Laura De Sciscio, Adrien Mahler…·Muriel Priault

DOI 10.64898/2026.05.14.725174

humanproteomics

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BiochemistryCell Death DiscoveryPeer-reviewedJul 23, 2024

The membrane insertion of the pro-apoptotic protein Bax is a Tom22-dependent multi-step process: a study in nanodiscs

Akandé Rouchidane Eyitayo, Laetitia Daury, Muriel Priault, Stéphen Manon

This study investigates Bax membrane insertion in nanodiscs, showing Tom22-dependent multi-step processes involving hydrophobic motifs and conformational changes.

11 citations

proteomicsexperimental assay

𝕏 PostBluesky