Isabel Prucker

This paper develops photocaged MSN analogues that can be delivered into E. coli, photo-released, and tracked to study their metabolic effects.

This study uses CE-MS to profile (p)ppGpp and dinucleoside polyphosphates in bacteria, revealing oscillatory dynamics and potential synchronization between alarmones.

This study identifies YohP as a small membrane protein in E. coli that induces membrane depolarization and (p)ppGpp accumulation, leading to metabolic silencing under stress.

This study characterizes two PPK2 enzymes, showing their broad substrate specificity and ability to selectively synthesize pyrimidine nucleoside diphosphates with high yield.