Author

Anna Shemorry

GenentechORCID 0000-0002-5797-3116Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Carrie R. GraveeliD· 1 shared Curt J. EssenburgiD· 1 shared Danilo MaddaloiD· 1 shared Elisia VillemureiD· 1 shared Elizabeth A. Tovar· 1 shared Elizabeth Levy· 1 shared Emily WolfrumiD· 1 shared Frank Peale· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Carrie R. GraveelORCID

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1 paper

Recent·Most cited

Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases

Anna Shemorry, Willem den Besten, Melinda M. Mulvihill, Curt J. Essenburg, Nicole Blaquière, Tracy Kleinheinz, Elisia Villemure, Frank Peale, Gauri S. Deshmukh, Danilo Maddalo, Elizabeth Levy, Kebing Yu, Matthew R. Steensma, Elizabeth A. Tovar, Emily Wolfrum, , Ingrid E. Wertz

This study evaluates bifunctional ER degraders with different ubiquitin ligase ligands, finding that pan-IAP antagonists enhance ER degradation and induce TNF-dependent cell death more effectively than existing therapies.

Cell chemical biology · May 1, 2025Peer-reviewedCancer Biology