Yang Liu

Molecular and network disruptions in neurodevelopment uncovered by single cell transcriptomics analysis of CHD8 heterozygous cerebral organoids

This study uses single-cell RNA-seq in cerebral organoids to analyze CHD8 heterozygous mutations, identifying altered gene expression, cell composition, and cell-cell communication linked to autism risk.

Single cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell deployment and progression

The paper uses single-cell RNA-sequencing to study how Tbx1 inactivation affects cardiac neural crest cell differentiation and aortic arch development in mice.

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in the murine cardiopharyngeal mesoderm

This study identifies a Tbx1-dependent multilineage primed population in the murine cardiopharyngeal mesoderm using single-cell RNA-sequencing and shows its role in cardiac and skeletal muscle development.

Spatiotemporal Gene Coexpression and Regulation in Mouse Cardiomyocytes of Early Cardiac Morphogenesis

The paper constructs gene co-expression networks in mouse cardiomyocytes to identify spatiotemporal gene modules and regulatory pathways involved in cardiac morphogenesis.