Christopher De Bono

This study shows that retinoic acid signaling in myocardium drives the formation of the muscular ventricular septum in mouse hearts, with defects leading to congenital heart defects.

The paper refines a human heart atlas using multi-modal data from the first trimester, identifying novel cell types and spatial features in cardiac development.

The paper uses single-cell RNA-sequencing to study how Tbx1 inactivation affects cardiac neural crest cell differentiation and aortic arch development in mice.

This study identifies a Tbx1-dependent multilineage primed population in the murine cardiopharyngeal mesoderm using single-cell RNA-sequencing and shows its role in cardiac and skeletal muscle development.

This study investigates the role of Hoxb1 in regulating cardiac progenitor cell patterning and differentiation, showing its negative regulation of posterior SHF differentiation and its impact on congenital heart defects.