Bin Zhou

The paper develops a transcriptome-based algorithm to estimate post-transcriptional gene regulation (PTGR) and applies it to brain RNA-Seq data from psychiatric disorders, revealing distinct PTGR dysregulation patterns across autism, schizophrenia, and bipolar disorder.

This paper shows that PROX1 inhibits PDGF-B expression in heart valves to prevent myxomatous degeneration, and PDGF-B inhibition ameliorates valve defects in mice.

This study shows that Crk and Crkl are essential for early angiogenesis in mouse embryos by regulating endothelial cell maturation and vascular remodeling.

This study identifies NFATc1 as a key regulator that negatively controls articular chondrocyte differentiation in mouse knee development.

The paper constructs gene co-expression networks in mouse cardiomyocytes to identify spatiotemporal gene modules and regulatory pathways involved in cardiac morphogenesis.