Alexander Ferrena

This study uses scRNA-seq to analyze murine osteosarcoma models and identifies Skp2's role in metastasis, genomic instability, and immune activation, revealing potential therapeutic targets.

This paper shows that binarizing scRNA-seq data and integrating it with scATAC-seq data using TF-IDF and LSI improves clustering for multiomic analysis.

This study shows aging reduces lung stem cell function and suppresses lung cancer by inducing iron deficiency through the NUPR1-lipocalin-2 pathway.

This study uses single-cell RNA sequencing to analyze the role of Six3 and Six6 in retinal progenitor cell differentiation, identifying altered developmental trajectories and gene regulation in their dual deficiency.

scDAPP provides an automated R-based pipeline for comparative single-cell transcriptomics analysis across groups, generating comprehensive results and visualizations.

The paper uses single-cell RNA-sequencing to study how Tbx1 inactivation affects cardiac neural crest cell differentiation and aortic arch development in mice.